LOS ANGELES -- Louie Anderson, whose four-decade career as a comedian and actor included his unlikely, Emmy-winning performance as mom to twin adult sons in the TV series "Baskets," died Friday. He was 68.
Anderson died at a hospital in Las Vegas of complications from cancer, said Glenn Schwartz, his longtime publicist. Anderson had a type of non-Hodgkin lymphoma, Schwartz said previously.
"'Baskets' was such a phenomenal 'second act' for Louie Anderson. I wish he'd gotten a third," Michael McKean said on Twitter. George Wallace wrote: "You'll be missed, Louie. What an awesome friend. One in a million." Gilbert Gottfried posted a photo of himself, Anderson and Bob Saget, who died Jan. 9, with the caption: "Both good friends that will be missed."
The portly, round-faced Anderson used his girth and a checkered childhood in Saint Paul, Minnesota, as fodder for his early stand-up routines.
In a 1987 interview with The Associated Press, Anderson compared himself to another comedian who mined his childhood for comedy.
"Bill Cosby and I had similar goals," Anderson told AP. "I wanted parents to be able to bring their children and children to be able to bring their parents to my concerts. I feel a family that can laugh about family problems is better off. The difference between Cosby and myself is that he sees it from an adult perspective and I tell it from a child's viewpoint."
He had a life-long battle with weight, but said in 1987 that he'd put a stop to using his size as stage material.
"I've always been big," he said. "But I don't do fat jokes anymore."
In later years, his life as one of 11 children in a family headed by a troubled father and devoted mother was a deeper source of reflection and inspiration for Anderson, both in his screen work and in his best-selling books.
His latest book, 2018's "Hey Mom," was a tribute in letters to the lessons he learned from her and how-to tips on facing life's challenges. He also gave the late Ora Zella Anderson a shout-out for the "Baskets" role.
"I just started writing with one letter, saying, 'Hey Mom, I'm playing you on TV. I hope you see it. I hope you're a part of it..." Anderson told AP that year.
He won the best supporting actor Emmy in 2016 for his portrayal of Christine Baskets, mother to twins played by Zach Galifianakis, in FX's "Baskets." Anderson, who received three consecutive Emmy nods for the role, played it with restraint and with specific touches he credits to his mom.
"Nuance is what I go for, tiny rather than bigger things. Mom did things with her eyes or her grimace or her disappointed lips -- or her passive-aggressiveness," he told the AP in 2015, laughing. "Rolling eyes were big in our family."
Anderson, born March 24, 1953, was the 10th of 11 children for Ora and William Anderson. His father played trumpet with musical great Hoagy Carmichael and, Anderson has said, was an alcoholic.
After his father's death, Anderson learned of how difficult his childhood had been and forgave him, he told People magazine in 2018.
Fellow performers recalled his gentleness. "You were as gracious and kind as you were funny. Rest well!! Keep 'em laughing in Heaven," Viola Davis said on Twitter. Rita Rudner in a statement, said: "He was a kind, generous, talented man who leaves behind a legacy of laughter, love and french fries."
His survivors include sisters Lisa and Shanna Anderson.